Murine Anti-Factor IX抗体(GMA-124)
货号：GMA-124
品牌：Greenmoab
产品特性
Specificity：Light chain of FIX/FIXa
Immunogen：Human Factor IX
Application：ELISA and Immunoblotting
| 规格 | 价格 |
|---|---|
| 0.1 mg | ￥咨询 |
| 0.5 mg | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：Murine Anti-Factor IX抗体(GMA-124)
别名：Murine Anti-Factor IX Antibody；Murine Anti-Factor IX Monoclonal Antibody；Murine Anti-Factor IX单克隆抗体；Factor IX抗体；Murine Anti-Factor IX抗体；小鼠抗凝血因子IX抗体；Mouse Anti-Factor IX Antibody；F9抗体
克隆号（Clone）：GMA-124
背景介绍（Background）：
Factor IX (FIX) is a vitamin K-dependent zymogen that plays an essential role in the coagulation cascade leading to thrombus formation. In the presence of calcium, activated Factor IX (FIXa) complexes with Factor VIIIa on phospholipid surfaces to create the tenase complex, which converts Factor X to its activated form. Absent or defective FIX is the cause of the X-linked recessive bleeding disorder hemophilia B. GMA-124 binds to FIX and detects the light chain of FIXa in both ELISA and Western blot formats. In addition, bound GMA-124 captures FIX by bio-layer interferometry.
种属反应性（Species Reactivity）: Bovine, Human, Porcine, Rat
来源（Source）： Murine
特异性（Specificity）： Light chain of FIX/FIXa
免疫原（Immunogen）： Human Factor IX
亚型（Isotype）： IgG1
应用（Application）：
ELISA： Binds immobilized Human, Rat, Porcine, and Bovine FIX, Human FIXa
Immunoblotting： Western blot detects Human FIX, light chain of Human FIXa under reduced conditions.
Inhibition： Does not prolong plasma clot time in APTT clotting assay.
BLI： KD=50 nM (kdis=4.38x10-3 sec-1) by bio-layer interferometry.
储存（Storage）：Aliquot and store at -20℃ for prolonged periods. Avoid freeze-thaw cycles. Alternatively, add 0.02% (w/v) sodium azide and store at 4℃.
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背景介绍（Background）：
Factor IX (FIX) is a vitamin K-dependent zymogen that plays an essential role in the coagulation cascade leading to thrombus formation. In the presence of calcium, activated Factor IX (FIXa) complexes with Factor VIIIa on phospholipid surfaces to create the tenase complex, which converts Factor X to its activated form. Absent or defective FIX is the cause of the X-linked recessive bleeding disorder hemophilia B. GMA-124 binds to FIX and detects the light chain of FIXa in both ELISA and Western blot formats. In addition, bound GMA-124 captures FIX by bio-layer interferometry.
种属反应性（Species Reactivity）: Bovine, Human, Porcine, Rat
来源（Source）： Murine
特异性（Specificity）： Light chain of FIX/FIXa
免疫原（Immunogen）： Human Factor IX
亚型（Isotype）： IgG1
应用（Application）：
ELISA： Binds immobilized Human, Rat, Porcine, and Bovine FIX, Human FIXa
Immunoblotting： Western blot detects Human FIX, light chain of Human FIXa under reduced conditions.
Inhibition： Does not prolong plasma clot time in APTT clotting assay.
BLI： KD=50 nM (kdis=4.38x10-3 sec-1) by bio-layer interferometry.
储存（Storage）：Aliquot and store at -20℃ for prolonged periods. Avoid freeze-thaw cycles. Alternatively, add 0.02% (w/v) sodium azide and store at 4℃.
