CD45抗体
货号：AB0100-200
品牌：SICGEN antibodies
产品特性
Application：WB
Purification：Epitope affinity purified
Reactivity：Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
Immunogen：Purified recombinant peptide derived from within residues 1,260 aa to the C-terminus of human CD45 produced in E. coli.
| 规格 | 价格 |
|---|---|
| 600 µg | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：CD45抗体
别名：Anti-CD45 Antibody；B220；CD45 antigen；CD45R；GP180；L-CA；LCA；leukocyte common antigen；LY5；protein tyrosine phosphatase；PTPRC；receptor type c polypeptide；receptor-type tyrosine-protein phosphatase C；RP11-553K8.4；T200；T200 glycoprotein；T200 leukocyte common antigen antibody.
SICGEN antibodies CD45抗体，Anti-CD45 Antibody，经验证适用于WB，众多文献引用。
描述（Description）：
Goat polyclonal antibody to CD45. It is a 180-220 kDa type I transmembrane glycoprotein and a member of the protein tyrosine phosphatase (PTP) family. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. It is expressed in all hematopoietic cells, but highest on lymphocytes. PTPs are known to be signalling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. It has intrinsic tyrosine phosphatase activity and it is essential for T and B cell antigen receptor-mediated activation. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signalling. CD45 also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signalling. The cross-linking of CD45 induces apoptosis in lymphocytes.
抗体浓度（Concentration）：3 mg/ml
抗体类型（Antibody Type）：一抗.
靶点名称（Target Name）：Anti-CD45
Accession Number：ENSG00000081237
来源（Source）：Goat
免疫原物种（Immunogen Species）：Human
免疫原类型（Immunogen Type）：Recombinant protein
免疫原（Immunogen）：Purified recombinant peptide derived from within residues 1,260 aa to the C-terminus of human CD45 produced in E. coli.
亚型（Isotype）：IgG
克隆性（Clonality）：Polyclonal
已验证反应物种（Confirmed Reactive Species）： Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
特异性细节（Specificity Detail）：Using Jurkat cell lysate detects a band 180-220 kDa by Western blot.
缓冲液（Buffer）：PBS, 20% glycerol and 0.05% sodium azide
纯化方式（Purification）：Epitope affinity purified
偶联（Conjugation）：Unconjugated
RRID：AB_2333126
应用（Application）：WB
稀释浓度（Dilution Concentration）：WB:1:500-1:2,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000
储存（Storage）：Store at -20 ℃ for long-term storage. Store at 2-8 ℃ for up to one month.
[注意事项]：勃谱生物销售的CD45抗体仅用于研究用途。不可用于诊断、医疗或其他用途。
[NOTICE]: Our products are for RESEARCH USE ONLY. Not for diagnostic, medical or other use.
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描述（Description）：
Goat polyclonal antibody to CD45. It is a 180-220 kDa type I transmembrane glycoprotein and a member of the protein tyrosine phosphatase (PTP) family. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. It is expressed in all hematopoietic cells, but highest on lymphocytes. PTPs are known to be signalling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. It has intrinsic tyrosine phosphatase activity and it is essential for T and B cell antigen receptor-mediated activation. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signalling. CD45 also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signalling. The cross-linking of CD45 induces apoptosis in lymphocytes.
抗体浓度（Concentration）：3 mg/ml
抗体类型（Antibody Type）：一抗.
靶点名称（Target Name）：Anti-CD45
Accession Number：ENSG00000081237
来源（Source）：Goat
免疫原物种（Immunogen Species）：Human
免疫原类型（Immunogen Type）：Recombinant protein
免疫原（Immunogen）：Purified recombinant peptide derived from within residues 1,260 aa to the C-terminus of human CD45 produced in E. coli.
亚型（Isotype）：IgG
克隆性（Clonality）：Polyclonal
已验证反应物种（Confirmed Reactive Species）： Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
特异性细节（Specificity Detail）：Using Jurkat cell lysate detects a band 180-220 kDa by Western blot.
缓冲液（Buffer）：PBS, 20% glycerol and 0.05% sodium azide
纯化方式（Purification）：Epitope affinity purified
偶联（Conjugation）：Unconjugated
RRID：AB_2333126
应用（Application）：WB
稀释浓度（Dilution Concentration）：WB:1:500-1:2,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000
储存（Storage）：Store at -20 ℃ for long-term storage. Store at 2-8 ℃ for up to one month.
[注意事项]：勃谱生物销售的CD45抗体仅用于研究用途。不可用于诊断、医疗或其他用途。
[NOTICE]: Our products are for RESEARCH USE ONLY. Not for diagnostic, medical or other use.
