CD45抗体, DyLight®633标记
货号：AB100633-100
品牌：SICGEN antibodies
产品特性
Source：Goat
Application：WB
Reactivity：Human, Rat, Mouse, Monkey, Canine
Immunogen：Purified recombinant peptide derived from within residues 1,260 aa to the C-terminus of human CD45 produced in E. coli.
Specificity：Using Jurkat cell lysate detects a band 180-220 kDa by Western blot.
| 规格 | 价格 |
|---|---|
| 250 µg | ￥咨询 |
产品咨询：info@biopcr.com
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详细介绍
产品名称：CD45抗体, DyLight®633标记
别名：Anti-CD45 Antibody, DyLight®633；Anti-CD45, DyLight®633；B220； CD45 antigen； CD45R； GP180； L-CA； LCA； leukocyte common antigen； LY5； protein tyrosine phosphatase； PTPRC； receptor type c polypeptide； receptor-type tyrosine-protein phosphatase C； RP11-553K8.4； T200； T200 glycoprotein； T200 leukocyte common antigen antibody；CD45抗体, DyLight®633标记
CD45抗体，Anti-CD45 Antibody， DyLight®633标记，经验证应用于WB检测。
来源（Source）： Goat
应用（Application）： WB
反应性（Reactivity）： Human, Rat, Mouse, Monkey, Canine
描述（Description）： Goat polyclonal antibody to CD45 conjugated to DyLight®633. It is a 180-220 kDa type I transmembrane glycoprotein and a member of the protein tyrosine phosphatase (PTP) family. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. It is expressed in all hematopoietic cells, but highest on lymphocytes. PTPs are known to be signalling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. It has intrinsic tyrosine phosphatase activity and it is essential for T and B cell antigen receptor-mediated activation. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signalling. CD45 also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signalling. The cross-linking of CD45 induces apoptosis in lymphocytes.
Gene Identifier/Accession#： Gene ID: 5788, ENSG00000081237
形式（Form）： Polyclonal antibody supplied as a 100 µl (2.5 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
抗体浓度（Concentration）： 2.50 mg/ml
稀释浓度（Dilution Concentration）：WB 1:1,000-1:5,000
亚型（Isotype）： IgG
克隆性（Clonality）： Polyclonal
偶联（Conjugation）： DyLight®633
免疫原（Immunogen）： Purified recombinant peptide derived from within residues 1,260 aa to the C-terminus of human CD45 produced in E. coli.
抗原序列（Antigen Sequence）： ANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPALNQGS
特异性（Specificity）： Using Jurkat cell lysate detects a band 180-220 kDa by Western blot.
储存（Storage）：Store at -20 ℃ for long-term storage. Store at 2-8 ℃ for up to one month.
特别说明（Special instructions）： Avoid freeze/thaw cycles.
[注意事项]：勃谱生物销售的CD45抗体, DyLight®633标记仅用于研究用途。不可用于诊断、医疗或其他用途。
[NOTICE]: Our products are for RESEARCH USE ONLY. Not for diagnostic, medical or other use.
返回列表
来源（Source）： Goat
应用（Application）： WB
反应性（Reactivity）： Human, Rat, Mouse, Monkey, Canine
描述（Description）： Goat polyclonal antibody to CD45 conjugated to DyLight®633. It is a 180-220 kDa type I transmembrane glycoprotein and a member of the protein tyrosine phosphatase (PTP) family. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. It is expressed in all hematopoietic cells, but highest on lymphocytes. PTPs are known to be signalling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. It has intrinsic tyrosine phosphatase activity and it is essential for T and B cell antigen receptor-mediated activation. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signalling. CD45 also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signalling. The cross-linking of CD45 induces apoptosis in lymphocytes.
Gene Identifier/Accession#： Gene ID: 5788, ENSG00000081237
形式（Form）： Polyclonal antibody supplied as a 100 µl (2.5 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
抗体浓度（Concentration）： 2.50 mg/ml
稀释浓度（Dilution Concentration）：WB 1:1,000-1:5,000
亚型（Isotype）： IgG
克隆性（Clonality）： Polyclonal
偶联（Conjugation）： DyLight®633
免疫原（Immunogen）： Purified recombinant peptide derived from within residues 1,260 aa to the C-terminus of human CD45 produced in E. coli.
抗原序列（Antigen Sequence）： ANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPALNQGS
特异性（Specificity）： Using Jurkat cell lysate detects a band 180-220 kDa by Western blot.
储存（Storage）：Store at -20 ℃ for long-term storage. Store at 2-8 ℃ for up to one month.
特别说明（Special instructions）： Avoid freeze/thaw cycles.
[注意事项]：勃谱生物销售的CD45抗体, DyLight®633标记仅用于研究用途。不可用于诊断、医疗或其他用途。
[NOTICE]: Our products are for RESEARCH USE ONLY. Not for diagnostic, medical or other use.
