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抗小鼠RANKL(IK22/5)体内抗体-低内毒素

货号:ICH1114-25mg 品牌:ichorbio

产品特性

Anti-Mouse RANKL (IK22/5) In Vivo Antibody - Low Endotoxin is manufactured in an cGMP compliant facility.
内毒素: <0.5 EU/mg as determined by the LAL method
纯度: >95% by SDS-PAGE and HPLC
应用: Flow Cytometry, Immunoprecipitation, Western Blot, Blocking, Immunofluorescence, IHC (Frozen).
规格 价格
25mg 咨询
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详细介绍

产品名称:抗小鼠RANKL(IK22/5)体内抗体-低内毒素
别名:抗小鼠RANKL体内抗体, 抗小鼠RANKL抗体-低内毒素, Anti-Mouse RANKL (IK22/5) In Vivo Antibody - Low Endotoxin, Anti-Mouse RANKL In Vivo Antibody, Anti-Mouse RANKL Antibody - Low Endotoxin, Tumor necrosis factor ligand superfamily member 11, Tnfsf11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TRANCE, CD254
宿主:Rat
应用:Flow Cytometry, Immunoprecipitation, Western Blot, Blocking, Immunofluorescence, IHC (Frozen)
亚型:Rat IgG2a Kappa
克隆:IK22/5
浓度:1.0 mg/ml
免疫原:Purified Recombinant Mouse RANKL (NSO-derived)
反应性:Mouse
特异性:Anti-RANKL In Vivo Antibody - Low Endotoxin (IK22/5) recognizes an epitope on Mouse RANKL
存储溶液:0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
储存条件:anti-RANKL In Vivo Antibody - Low Endotoxin (IK22/5) is stable when stored at 2-8°C. Do not freeze.This antibody is
推荐同型对照(Isotype Control):Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): RANKL
UniProt:O35235
纯化方法(Purification method): This monoclonal antibody was purified using Protein G
背景资料(Background):RANKL (Receptor Activator for Nuclear Factor κ B Ligand), also known as TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and ODF (osteoclast differentiation factor), is a member of the tumor necrosis factor family cytokine. RANKL is essential for osteoclast formation, activation, and survival. RANKL through interaction with its receptor RANK can modulate matrix degradation and inflammation. RANKL and RANK have essential roles in lymph node formation, establishment of the thymic microenvironment, and development of a lactating mammary gland during pregnancy. Consequently, novel drugs specifically targeting RANK, RANKL, and their signaling pathways in osteoclasts are expected to revolutionize the treatment of various ailments associated with bone loss, such as arthritis, periodontal disease, cancer metastases, and osteoporosis.
纯度(Purity):>95% by SDS-PAGE and HPLC
内毒素(Endotoxin):<0.5 EU/mg as determined by the LAL method
聚集(Aggregation):Aggregation level ≤ 5%
应用说明(Application Notes):Each investigator should determine their own optimal working dilution for specific applications.
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice
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