抗小鼠IL-1R(JAMA-147)体内抗体-低内毒素
货号:ICH1117-5mg
品牌:ichorbio
产品特性
Anti-Mouse IL-1R (JAMA-147) In Vivo Antibody - Low Endotoxin is manufactured in an cGMP compliant facility.
内毒素: ≤ 1.0 EU/mg as determined by the LAL method
纯度: >95% by SDS-PAGE and HPLC
应用: Immunoprecipitation, Western Blot, Blocking, Flow Cytometry.
规格 | 价格 |
---|---|
5mg | ¥咨询 |
产品咨询:info@biopcr.com
产品订购:sales@biopcr.com
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服务热线:400-860-6200
详细介绍
产品名称:抗小鼠IL-1R(JAMA-147)体内抗体-低内毒素
别名:抗小鼠IL-1R体内抗体, 抗小鼠IL-1R抗体-低内毒素, Anti-Mouse IL-1R (JAMA-147) In Vivo Antibody - Low Endotoxin, Anti-Mouse IL-1R In Vivo Antibody, Anti-Mouse IL-1R Antibody - Low Endotoxin, Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha,
IL-1R-alpha, Interleukin-1 receptor type I, p80, CD121a
宿主:Armenian Hamster
应用:Immunoprecipitation, Western Blot, Blocking, Flow Cytometry
亚型:Armenian Hamster IgG
克隆:JAMA-147
浓度:1.0 - 5.0 mg/ml
免疫原:Extracellular domain of mouse IL-1 R type 1
反应性:Mouse
特异性:Anti-IL-1R In Vivo Antibody - Low Endotoxin (JAMA-147) recognizes Mouse IL-1 R1
存储溶液:0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
储存条件:anti-IL-1R In Vivo Antibody - Low Endotoxin (JAMA-147) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles
推荐同型对照(Isotype Control):Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251)
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): IL1R1
UniProt:P13504
纯化方法(Purification method): This monoclonal antibody was purified using Protein A
背景资料(Background):IL-1 binds two receptors, IL-1RI and IL-1RII. The ligands IL-1alpha and IL-1beta exert all of their various biological actions by binding IL-1RI. IL-1RII has a shortened cytoplasmic domain that is unable to transduce signals and therefore acts as a decoy receptor and competitively antagonizes the binding of IL-1alpha and IL-1beta, thereby reducing their biological effects. Binding of the ligands to IL-1RI is enhanced by an accessory protein, IL-1R-AcP. IL-1RI is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. It is an 80 kD transmembrane glycoprotein.
纯度(Purity):>95% by SDS-PAGE and HPLC
内毒素(Endotoxin):≤ 1.0 EU/mg as determined by the LAL method
聚集(Aggregation):Aggregation level ≤ 5%
应用说明(Application Notes):Each investigator should determine their own optimal working dilution for specific applications.
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice
返回列表
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): IL1R1
UniProt:P13504
纯化方法(Purification method): This monoclonal antibody was purified using Protein A
背景资料(Background):IL-1 binds two receptors, IL-1RI and IL-1RII. The ligands IL-1alpha and IL-1beta exert all of their various biological actions by binding IL-1RI. IL-1RII has a shortened cytoplasmic domain that is unable to transduce signals and therefore acts as a decoy receptor and competitively antagonizes the binding of IL-1alpha and IL-1beta, thereby reducing their biological effects. Binding of the ligands to IL-1RI is enhanced by an accessory protein, IL-1R-AcP. IL-1RI is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. It is an 80 kD transmembrane glycoprotein.
纯度(Purity):>95% by SDS-PAGE and HPLC
内毒素(Endotoxin):≤ 1.0 EU/mg as determined by the LAL method
聚集(Aggregation):Aggregation level ≤ 5%
应用说明(Application Notes):Each investigator should determine their own optimal working dilution for specific applications.
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice