抗小鼠Galectin-9(RG9-1)体内抗体-低内毒素
货号：ICH1186-25mg
品牌：ichorbio
产品特性
Anti-Mouse Galectin-9 (RG9-1) In Vivo Antibody - Low Endotoxin is manufactured in an cGMP compliant facility.
内毒素: <1.0 EU/mg as determined by the LAL method
纯度: ≥95% monomer by analytical SEC, >95% by SDS-PAGE
应用: Blocking.
| 规格 | 价格 |
|---|---|
| 25mg | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：抗小鼠Galectin-9(RG9-1)体内抗体-低内毒素
别名：抗小鼠Galectin-9体内抗体, 抗小鼠Galectin-9抗体-低内毒素, Anti-Mouse Galectin-9 (RG9-1) In Vivo Antibody - Low Endotoxin, Anti-Mouse Galectin-9 In Vivo Antibody, Anti-Mouse Galectin-9 Antibody - Low Endotoxin, Gal-9
宿主：Rat
应用：Blocking
亚型：Rat IgG2b Kappa
克隆：RG9-1
浓度：≥ 5.0 mg/ml
免疫原：Recombinant mouse galectin-9
反应性：Mouse
特异性：RG9-1 activity is directed against mouse galectin-9
存储溶液：This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
储存条件：This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
推荐同型对照（Isotype Control）：Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243)
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0；体内抗体缓冲液pH7.4；体内抗体缓冲液pH8.0
靶点（Target）: Galectin-9
UniProt：O08573
纯化方法（Purification method）: This monoclonal antibody was purified using Protein G
抗原分布（Antigen Distribution）：Galectin-9 is expressed by many cell types, including T cells, B cells, macrophages, dendritic cells, astrocytes, mast cells, eosinophils, fibroblasts, endothelial cells, and epithelial cells
背景资料（Background）：Galectin-9 (Gal-9), a member of the galectin family of mammalian lectins, binds β-galactoside. Gal-9 is expressed by many cell types, including endothelial cells, the epithelium of the gastrointestinal tract, T cells, B cells, macrophages, and mast cells. Gal-9 plays a significant role in innate and adaptive immunity and regulates excessive immunity by suppressing interleukin (IL)-17 producing effector T helper cells (Th)17 and Th1 as well as by augmenting Foxp3+ regulatory T cells (Treg). In addition, Gal-9 induces monocytic myeloid-derived suppressor cells (MDSCs), granulocytic MDSCs, and plasmacytoid dendritic cell-like macrophages. Gal-9 also suppresses B cell receptor signaling and is regulated by I-branching of N-glycans. Additionally, Gal-9 stimulates the maturation of dendritic cells.Gal-9 is thought to function by binding to specific carbohydrate moieties in receptor molecules expressed on the surface of its target cells, including the T-cell immunoglobulin- and mucin-domain-containing molecule-3 (Tim-3)1. Gal-9 is predominantly located in the cytoplasm but can also be secreted. Gal-9 is expressed by a variety of tumor cells, plays a role in tumor immunity, and can suppress tumor metastasis by blocking adhesion to endothelium and extracellular matrices. CD45, which regulates antigen receptor signaling, is a major glycoprotein receptor for Gal-9 on naive B cells.
纯度（Purity）：≥95% monomer by analytical SEC, >95% by SDS-PAGE
内毒素（Endotoxin）：<1.0 EU/mg as determined by the LAL method
聚集（Aggregation）：Aggregation level ≤ 5%
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
返回列表
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0；体内抗体缓冲液pH7.4；体内抗体缓冲液pH8.0
靶点（Target）: Galectin-9
UniProt：O08573
纯化方法（Purification method）: This monoclonal antibody was purified using Protein G
抗原分布（Antigen Distribution）：Galectin-9 is expressed by many cell types, including T cells, B cells, macrophages, dendritic cells, astrocytes, mast cells, eosinophils, fibroblasts, endothelial cells, and epithelial cells
背景资料（Background）：Galectin-9 (Gal-9), a member of the galectin family of mammalian lectins, binds β-galactoside. Gal-9 is expressed by many cell types, including endothelial cells, the epithelium of the gastrointestinal tract, T cells, B cells, macrophages, and mast cells. Gal-9 plays a significant role in innate and adaptive immunity and regulates excessive immunity by suppressing interleukin (IL)-17 producing effector T helper cells (Th)17 and Th1 as well as by augmenting Foxp3+ regulatory T cells (Treg). In addition, Gal-9 induces monocytic myeloid-derived suppressor cells (MDSCs), granulocytic MDSCs, and plasmacytoid dendritic cell-like macrophages. Gal-9 also suppresses B cell receptor signaling and is regulated by I-branching of N-glycans. Additionally, Gal-9 stimulates the maturation of dendritic cells.Gal-9 is thought to function by binding to specific carbohydrate moieties in receptor molecules expressed on the surface of its target cells, including the T-cell immunoglobulin- and mucin-domain-containing molecule-3 (Tim-3)1. Gal-9 is predominantly located in the cytoplasm but can also be secreted. Gal-9 is expressed by a variety of tumor cells, plays a role in tumor immunity, and can suppress tumor metastasis by blocking adhesion to endothelium and extracellular matrices. CD45, which regulates antigen receptor signaling, is a major glycoprotein receptor for Gal-9 on naive B cells.
纯度（Purity）：≥95% monomer by analytical SEC, >95% by SDS-PAGE
内毒素（Endotoxin）：<1.0 EU/mg as determined by the LAL method
聚集（Aggregation）：Aggregation level ≤ 5%
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
