产品特性
Anti Dityrosine (DT) monoclonal antibody
抗原：3-(p-hydroxyphenyl) propionic acid dimer-conjugated keyhole limpet hemocyanin；纯化：经蛋白A纯化
该抗体对二酪氨酸具有高度特异性，可与游离二酪氨酸以及含二酪氨酸的蛋白质或肽发生反应
Suitable for immunohistocheistry, western blotting and ELISA.
| 规格 | 价格 |
|---|---|
| 20 µg | ￥咨询 |
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详细介绍
产品名称：Dityrosine(DT)抗体
别名：Anti Dityrosine monoclonal antibody; Anti Dityrosine antibody; Anti DT monoclonal antibody; Anti DT antibody; Dityrosine抗体; DT抗体; 双酪氨酸抗体; 抗二酪氨酸抗体; 抗二酪氨酸单克隆抗体
应用：Immunohistochemistry, western blotting and ELISA
克隆：1C3
储存条件：Less than -20°C
蛋白质氧化的新型生物标志物：
Tyrosine is one of the major targets of protein oxidation, and until today various tyrosine derivatives such as nitrotyrosine, dityrosine and halogenated tyrosine depending on the type of free radicals. DT is a tyrosine dimer derived from tyrosyl radicals which is formed by reactive oxygen species (ROS), metal-catalyzed oxidation, ultraviolet irradiation, and peroxidases. DT have been found in atherosclerotic lesions, and lipofuscin of pyramidal neurons of aged human brains. Dityrosine is one of the specific biomarkers for protein oxidation.
蛋白质样品中二酪氨酸（DT）的检测：
Anti dityrosine monoclonal antibody clone 1C3 has been established by Dr. Toshihiko Osawa (Nagoya Univ.) and Dr. Yoji Kato (Univ. Hyogo)1). They have prepared this antibody using a dimer of 3-(p-hydroxyphenyl) propionic acid as a hapten, and screened using dityrosine-conjugated BSA. This antibody is highly specific for dityrosine, and can react with both free dityrosine and dityrosine containing protein or peptides. Suitable for immunohistochemistry, western blotting and ELISA.
抗原： 3-(p-hydroxyphenyl) propionic acid dimer-conjugated keyhole limpet hemocyanin.
形式： Lyophilized power. Reconstitute by 200 µL of distilled water. 100 µg/mL of IgG.
亚类： Mouse IgG2a(kappa).
纯化：Protein A purified.
特异性： Specific for free dityrosine, 3-(p-hydroxyphenyl) propionic acid dimer, dityrosine-BSA conjugate, and dityrosine in protein or peptides. Cross reactivity have been tested for following analogues: Nitrotyrosine, chlorotyrosine, aminotyrosine, phosphotyrosine, tyrosine, 3-(p-hydroxyphenyl) propionic acid, phenylalanine, 3,4-dihydroxyphenylacetic acid (DOPA)
[注意事项]：我们的抗二酪氨酸（Dityrosine）单克隆抗体仅用于研究用途。不可用于诊断、医疗或其他用途。
[NOTICE]: Our products are for RESEARCH USE ONLY. Not for diagnostic, medical or other use.
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Tyrosine is one of the major targets of protein oxidation, and until today various tyrosine derivatives such as nitrotyrosine, dityrosine and halogenated tyrosine depending on the type of free radicals. DT is a tyrosine dimer derived from tyrosyl radicals which is formed by reactive oxygen species (ROS), metal-catalyzed oxidation, ultraviolet irradiation, and peroxidases. DT have been found in atherosclerotic lesions, and lipofuscin of pyramidal neurons of aged human brains. Dityrosine is one of the specific biomarkers for protein oxidation.
蛋白质样品中二酪氨酸（DT）的检测：
Anti dityrosine monoclonal antibody clone 1C3 has been established by Dr. Toshihiko Osawa (Nagoya Univ.) and Dr. Yoji Kato (Univ. Hyogo)1). They have prepared this antibody using a dimer of 3-(p-hydroxyphenyl) propionic acid as a hapten, and screened using dityrosine-conjugated BSA. This antibody is highly specific for dityrosine, and can react with both free dityrosine and dityrosine containing protein or peptides. Suitable for immunohistochemistry, western blotting and ELISA.
抗原： 3-(p-hydroxyphenyl) propionic acid dimer-conjugated keyhole limpet hemocyanin.
形式： Lyophilized power. Reconstitute by 200 µL of distilled water. 100 µg/mL of IgG.
亚类： Mouse IgG2a(kappa).
纯化：Protein A purified.
特异性： Specific for free dityrosine, 3-(p-hydroxyphenyl) propionic acid dimer, dityrosine-BSA conjugate, and dityrosine in protein or peptides. Cross reactivity have been tested for following analogues: Nitrotyrosine, chlorotyrosine, aminotyrosine, phosphotyrosine, tyrosine, 3-(p-hydroxyphenyl) propionic acid, phenylalanine, 3,4-dihydroxyphenylacetic acid (DOPA)
[注意事项]：我们的抗二酪氨酸（Dityrosine）单克隆抗体仅用于研究用途。不可用于诊断、医疗或其他用途。
[NOTICE]: Our products are for RESEARCH USE ONLY. Not for diagnostic, medical or other use.
