TAT复合物抗体对
货号：TAT-EIA
品牌：Affinity Biologicals
产品特性
TAT Complex Paired Antibody Set
抗体对包含捕获抗体和检测抗体
抗体经过严格的滴定和优化
适用于夹心ELISA检测
| 规格 | 价格 |
|---|---|
| 5 plates | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：TAT复合物抗体对
别名：TAT Complex Paired Antibody Set；凝血酶-抗凝血酶复合物抗体对；Thrombin-Antithrombin复合物抗体对；TAT Complex抗体对；凝血酶-抗凝血酶复合物配对抗体；TAT Complex配对抗体
应用：夹心法ELISA检测
形式：液体
储存条件：储存于2°C-8°C
Affinity Biologicals TAT Complex Paired Antibody Set抗体对由匹配的捕获抗体和检测抗体组成，抗体已经过滴定和优化用于夹心ELISA检测。
TAT复合物抗体对包含有足够5 x 96孔板使用的捕获抗体和检测抗体，提供有详细的操作说明，溶液配方和所需其他材料的来源。
Factor IX抗体对旨在用于实验室建立研究目的的内部免疫测定，不能用于诊断应用。
TAT Complex抗体对组分：
Capture Antibody(TAT-EIA-C): 1 x 0.5 mL多克隆亲和纯化anti-thrombin antibody, 用于包被板。
Detecting Antibody(TAT-EIA-D): 1 x 0.5 mL过氧化物酶标记亲和纯化的多克隆anti-ATIII antibody, 用于检测捕获的TAT复合物。
Conjugate Diluent:5 x 10 mL, 每管含10 mL过氧化物酶偶联抗体通用稀释液。每管足够一个96孔板使用。
描述：
The activation of coagulation ultimately leads to the activation of prothrombin to the enzyme thrombin. Unless regulated, thrombin will act on its natural substrates that include fibrinogen, factor V, factor VIII, factor XIII, Protein C, TAFI as well as specific receptors on platelets and endothelial cells. The activity of thrombin in plasma is regulated in part through interaction with protease inhibitors. Based on kinetic rates and physiological concentrations, the primary inhibitor of thrombin in plasma is antithrombin (ATIII), followed by heparin cofactor II and alpha-2-macroglobulin.The thrombin-antithrombin complex (TAT) results when thrombin cleaves a scissile bond near the C-terminus of ATIII, forming a covalent, 1:1 acyl enzyme intermediate with ATIII with an apparent mass of 96 kDa. Calcium is not required for this interaction, but the rate of thrombin inhibition by ATIII can be accelerated 1000-fold by optimal concentrations of heparin. Although TAT complex is relatively stable, under conditions of elevated pH and/or enzyme excess, enzymatic degradation and even dissociation of the complex can occur. In serum, vitronectin (also known as S-Protein) has been reported to form larger ternary complexes with TAT (350 kDa), but these ternary S-TAT complexes are not covalently linked and are not stable to denaturants such as SDS. TAT complex is cleared from circulation by serpin-enzyme complex receptors on the surface of hepatocytes, with a half-life of 15 minutes.
返回列表
TAT复合物抗体对包含有足够5 x 96孔板使用的捕获抗体和检测抗体，提供有详细的操作说明，溶液配方和所需其他材料的来源。
Factor IX抗体对旨在用于实验室建立研究目的的内部免疫测定，不能用于诊断应用。
TAT Complex抗体对组分：
Capture Antibody(TAT-EIA-C): 1 x 0.5 mL多克隆亲和纯化anti-thrombin antibody, 用于包被板。
Detecting Antibody(TAT-EIA-D): 1 x 0.5 mL过氧化物酶标记亲和纯化的多克隆anti-ATIII antibody, 用于检测捕获的TAT复合物。
Conjugate Diluent:5 x 10 mL, 每管含10 mL过氧化物酶偶联抗体通用稀释液。每管足够一个96孔板使用。
描述：
The activation of coagulation ultimately leads to the activation of prothrombin to the enzyme thrombin. Unless regulated, thrombin will act on its natural substrates that include fibrinogen, factor V, factor VIII, factor XIII, Protein C, TAFI as well as specific receptors on platelets and endothelial cells. The activity of thrombin in plasma is regulated in part through interaction with protease inhibitors. Based on kinetic rates and physiological concentrations, the primary inhibitor of thrombin in plasma is antithrombin (ATIII), followed by heparin cofactor II and alpha-2-macroglobulin.The thrombin-antithrombin complex (TAT) results when thrombin cleaves a scissile bond near the C-terminus of ATIII, forming a covalent, 1:1 acyl enzyme intermediate with ATIII with an apparent mass of 96 kDa. Calcium is not required for this interaction, but the rate of thrombin inhibition by ATIII can be accelerated 1000-fold by optimal concentrations of heparin. Although TAT complex is relatively stable, under conditions of elevated pH and/or enzyme excess, enzymatic degradation and even dissociation of the complex can occur. In serum, vitronectin (also known as S-Protein) has been reported to form larger ternary complexes with TAT (350 kDa), but these ternary S-TAT complexes are not covalently linked and are not stable to denaturants such as SDS. TAT complex is cleared from circulation by serpin-enzyme complex receptors on the surface of hepatocytes, with a half-life of 15 minutes.
